1.Wenhao Dai#, Bing Zhang#, Xia-Ming Jiang#, Haixia Su#, Jian Li, Yao Zhao, Xiong Xie, Zhenming Jin, Jingjing Peng, Fengjiang Liu, Chunpu Li, You Li, Fang Bai, Haofeng Wang, Xi Cheng, Xiaobo Cen, Shulei Hu, Xiuna Yang, Jiang Wang, Xiang Liu, Gengfu Xiao, Hualiang Jiang, Zihe Rao, Lei-Ke Zhang*, Yechun Xu*, Haitao Yang*, Hong Liu*. Structure-Based Design of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease. Science. 2020, DOI: 10.1126/science.abb4489.
2.Yichu Liu, Yibing Wang, Wenhao Dai, Wei Huang, Yingxia Li* and Hong Liu*. Palladium-Catalysed C(sp3)-H Glycosylation for Synthesis of C-Alkyl Glycoamino Acids. Angewandte Chemie International Edition. 2020, 59, 3491-3494.
3.Xingjun Li#, Jiang Wang#, Xiong Xie, Wenhao Dai, Xu Han, Kaixian Chen* and Hong Liu*. Ir(III)-Catalyzed direct C-H functionalization of N-phenylacetamide with α-diazo quinones: a novel strategy for producing 2-hydroxy-2’amino-1,2’-biaryl scaffolds. Chemical Communications. 2020, 56, 3441-3444.
4.Jingjing Peng, Chunpu Li, Mirzadavlat Khamrakulov, Jiang Wang* and Hong Liu*. Rhodium(III)-Catalyzed C-H Alkenylation: Access to Maleimide-Decorated Tryptophan and Tryptophan-Containing Peptides. Organic Letters. 2020, 22, 1535-1541.
5.Xuewu Liang, Jie Zang, Xiaoyang Li, Shuai Tang, Min Huang, Meiyu Geng, C. James Chou, Chunpu Li, Yichun Cao, Wenfang Xu, Hong Liu,* and Yingjie Zhang*. Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies. Journal of Medicinal Chemistry. 2019, 62, 3898-3923.
6.Yibing Wang, Hong Liu*. A Drug with Lipophilicity-dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-inflammatory Agent. Journal of Medicinal Chemistry. 2018, 61, 10412-10414.
7.Panfeng Peng, Huan Chen, Ya Zhu, Zhilong Wang, Jian Li, Rong-Hua Luo,Jiang Wang, Liang Chen, Liu-Meng Yang, Hualiang Jiang, Xin Xie,Beili Wu*, Yong-Tang Zheng*,and Hong Liu*.Structure -Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists. Journal of Medicinal Chemistry. 2018, 61, 9621-9636.
8.Jianhui Zhou, Jian Li, Yazhou Li, Chenglin Wu, Guoxue He, Qiaolan Yang, Yu Zhou* and Hong Liu*.Direct Synthesis of 3-Acylindoles through Rhodium(III)-Catalyzed Annulation of N-Phenylamidines with α-Cl Ketones. Organic Letters. 2018, 20, 7645-7649.
9.Feifei Fang, Chunmei Zhang, Chaofan Zhou, Yazhou Li, Yu Zhou,* and Hong Liu*. Rh(III)-Catalyzed C-H Activation of Benzoylacetonitriles and Tandem Cyclization with Diazo Compounds to Substituted Benzo[de]chromenes. Organic letters. 2018, 20, 1720-1724.
10.Xiaowei Wu, Bao Wang, Shengbin Zhou, Yu Zhou,* and Hong Liu*. Ruthenium-Catalyzed Redox-Neutral [4+1] Annulation of Benzamides and Propargyl Alcohols via C-H Bond Activation. ACS catalysis. 2017, 7, 2494-2499.
11.Wei Zhu, Hui Chen, Yulan Wang, Jiang Wang, Xia Peng, Xianjie Chen, Yinglei Gao, Yulong He, Jing Ai*, Meiyu Geng, Mingyue Zheng* and Hong Liu*. Design, Synthesis, and Pharmacological Evaluation of Novel Multi-substituted Pyridin-3-amine Derivatives as Multi-Targeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer. Journal of Medicinal Chemistry. 2017, 60, 6018-6035.
12.Xiaowei Wu, Bao Wang, Yu Zhou,and Hong Liu*. Propargyl alcohols as one-carbon synthons: redox-neutral Rh (III)-catalyzed C-H bond activation for the synthesis of isoindolinones bearing a quaternary carbon. Organic Letters. 2017, 19, 1294-1297.
13.Yu Zhou, Jiang Wang, Zhanni Gu, Shuni Wang, Wei Zhu, Jose Luis Acena,* Vadim A. Soloshonok,* Kunisuke Izawa,* and Hong Liu*. Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II- III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas. Chemical Reviews. 2016, 116, 422-518.
14.Fei Zhao, Jing Li, Ying Chen, Yanxin Tian, Chenglin Wu, Yanan Xie, Yu Zhou, Jiang Wang, Xin Xie,* and Hong Liu*. Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α1A-Adrenoceptor Antagonists. Journal of Medicinal Chemistry. 2016, 59, 3826-3839.
15.Diliang Guo, Jing Li, Henry Lin, Yu Zhou, Ying Chen, Fei Zhao, Haifeng Sun, Dan Zhang, Honglin Li, Brian K. Shoichet, Lei Shan, Weidong Zhang, Xin Xie,* Hualiang Jiang,* Hong Liu*. Design, Synthesis and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective α1A-Adrenoceptor Antagonists. Journal of Medicinal Chemistry. 2016, 59, 9489-9502.
16.Panfeng Peng, Jiang Wang, Hualiang Jiang,and Hong Liu*. Rhodium(III)-Catalyzed Site-Selective C-H Alkylation and Arylation of Pyridones Using Organoboron Reagents. Organic Letters. 2016, 18, 5376-5379.
17.Yong Nian, Jiang Wang, Shengbin Zhou, Shuni Wang, Hiroki Moriwaki, Aki Kawashima, Vadim A. Soloshonok,* and Hong Liu*. Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging α-Amino Acids. Angewandte Chemie International Edition. 2015, 54, 12918–12922.
18.Xiaowei Wu, Dengyou Zhang, Shengbin Zhou, Feng Gao and Hong Liu*. Site-specific indolation of proline-based peptides via copper(II)-catalyzed oxidative coupling of tertiary amine N-oxides. Chemical Communications. 2015, 51, 12571-12573.
19.Dengyou Zhang, Feng Gao, Yong Nian, Yu Zhou, Hualiang Jiang, and Hong Liu*. Palladium-Catalyzed Picolinamide-Directed Coupling of C(sp2)-H and C(sp2)-H: a Straightforward Approach to Quinolinone and Pyridone Scaffolds. Chemical Communications. 2015, 51, 7509 -7511.
20.Jiang Wang, María Sanchez-Rosello, Jose? Luis Acen?a, Carlos del Pozo, Alexander E. Sorochinsky, Santos Fustero*, Vadim A. Soloshonok,* Hong Liu*. Fluorine in Pharmaceutical Industry: Fluorinated Drugs Introduced to the Market in the Last Decade. Chemical Reviews. 2014,114, 2432-2506.
21.Shengbin Zhou, Jiang Wang, Xia Chen, Jose Luis Acena ,Vadim A. Soloshonok,* and Hong Liu*. Chemical Kinetic Resolution of Unprotected b-Substituted-b-Amino Acids Using Recyclable Chiral Ligands. Angewandte Chemie International Edition. 2014, 53, 7883-7886.
22.Ryosuke Takeda, Akie Kawamura, Aki Kawashima, Tatsunori Sato, Hiroki Moriwaki*, Kunisuke Izawa, Kenichi Akaji, Shuni Wang, Hong Liu,* Jose Luis Acena, and Vadim A. Soloshonok*. Chemical Dynamic Kinetic Resolution and S/R Interconversion of Unprotected a-Amino Acids. Angewandte Chemie International Edition. 2014,53, 12214-12217.
23.Hao Cai, Yu Zhou, Dong Zhang, Jinyi Xu*, and Hong Liu*. A Mannich/Cyclization Cascade Process for the Asymmetric Synthesis of Spirocyclic Thioimida-zolidinexoindoles. Chemical Communications. 2014, 50, 14771-14774.
24.Enguang Feng, Woo-Jin Shin, Xuelian Zhu, Jian Li, Deju Ye, Jiang Wang, Jian-Ping Zuo, Kyoung Tai No, Mingyue Zheng, Weiliang Zhu, * Wei Tang, * Baik-Lin Seong,* Hualiang Jiang, and Hong Liu*. Structure-Based Design, Synthesis of C-1 and C-4 modified analogs of zanamivir as neuraminidase inhibitors. Journal of Medicinal Chemistry. 2013, 56, 671-684.
25.Shengtao Xu, Yu Zhou, Jinyi Xu*, Hualiang Jiang, and Hong Liu*. Gold-catalyzed Michael Addition/Intramolecular Annulation Cascade: an Effective Pathway for the Chemoselective- and Regioselective Synthesis of Tetracyclic Indole Derivatives in Water. Green Chemistry. 2013,15,718-726.