cas_call({"xm":"韩海浩","xb":"男","zc":"副研究员","xl":"博士","dh":"","cz":"","dzyj":"hanhaihao@simm.ac.cn","grzy":"","zjlb":"研究员","zw":"青年课题组长","txdz":"烟台市高新区滨海东路198号","grjj":"
韩海浩，中国科学院上海药物研究所\/中科环渤海（烟台）药物高等研究院副研究员，青年课题组长，中国化学会会员。2020年6月于华东理工大学获工学博士学位，2020年7月-2022年6月于华东理工大学化学博士后科研流动站从事博士后研究工作。迄今已发表SCI论文30余篇，其中以共同通讯或第一（含共一）作者在J. Am. Chem. Soc., Chem. Sci., Theranostics, Sci. Bull., Chem. Soc. Rev., Coord. Chem. Rev<\/i><\/font>.等国内外知名期刊发表论文19篇，总引用> 1400，h指数15。曾获山东省优秀毕业生、博士研究生国家奖学金、高水平期刊论文奖、第五届世界诊疗大会旅行奖等奖励。作为项目负责人，主持了国家自然科学基金青年科学基金，中国博士后科学基金第68批面上资助，以及华东理工大学首届“张江树”优博培育计划等项目。近期，受邀担任《Frontier in Chemistry》国际期刊评审编辑（Review Editor），同时长期担任英国皇家化学会国际期刊同行评议员。<\/div>\n
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教育经历：<\/b>　<\/div>\n
1. 2015.09-2020.06，华东理工大学，应用化学，硕博<\/div>\n2. 2011.09-2015.06，山东理工大学，应用化学，本科 ","yjfx":"
1. 恶性肿瘤和代谢性疾病演进过程中生物大分子动态修饰的化学探测；<\/div>\n
2. 恶性肿瘤和代谢性疾病的光学、多模态成像与治疗一体化新材料创制；<\/div>\n3. 人类重大疾病的糖靶向药研发与临床转化。 ","dblz":"
1.Hai-Hao Han<\/b>, He Tian Jr., Yi Zang, Adam C Sedgwick, Jia Li*, Jonathan L Sessler*, Xiao-Peng He*, Tony D. James*. Small-molecule fluorescence-based probes for interrogating major organ diseases. Chemical Society Reviews<\/i>. 2021, 50: (17), 9391-9429. <\/font><\/div>\n
2.Hai-Hao Han<\/b>#<\/sup>, Adam C Sedgwick#<\/sup>, Ying Shang#<\/sup>, Na Li, Tingting Liu, Bo-Han Li, Kunqian Yu, Yi Zang, James T Brewster, Maria L Odyniec, Maria Weber, Steven D Bull, Jia Li*, Jonathan L Sessler*, Tony D James*, Xiao-Peng He*, He Tian. Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes. Chemical Scienc<\/i>e. 2020, 11, 1107-1113<\/font><\/div>\n
3.Hai-Hao Han<\/b><\/font>#<\/sup><\/span>, Yu-Jiao Qiu<\/span>#<\/sup><\/span>, Yuan-Yuan Shi<\/span>#<\/sup><\/span>, Wen Wen, Xiao-Peng He*, Li-Wei Dong*, Ye-Xiong Tan*, Yi-Tao Long, He Tian, Hong-Yang Wang*. Glypican-3-targeted precision diagnosis of hepatocellular carcinoma on clinical sections with a supramolecular 2D imaging probe.<\/span> Theranostics.<\/i> 2018, 8: (12), 3268. <\/span><\/div>\n
4.Xianzhi Chai<\/font>#<\/sup><\/span>, <\/span>Hai-Hao Han<\/b>#<\/sup><\/span>, Adam C. Sedgwick<\/span>#<\/sup><\/span>, Na Li, Yi Zang, Tony D. James, Junji Zhang*, Xi-Le Hu, Yang Yu, Yao Li, Yan Wang, Jia Li*, Xiao-Peng He*, He Tian. Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers. <\/span>Journal of the American Chemical Society<\/i>. 2020, 142: (42), 18005-18013. <\/span><\/div>\n
5.Youxin Fu<\/font>#<\/sup><\/span>, <\/span>Hai-Hao Han<\/b>#<\/sup><\/span>, Junji Zhang*, Xiao-Peng He*, Ben L Feringa, He Tian*. Photocontrolled fluorescence “double-check” bioimaging enabled by a glycoprobe–protein hybrid. <\/span>Journal of the American Chemical Society<\/i>. 2018, 140: (28), 8671-8674. <\/span><\/div>\n
6.Hai-Hao Han<\/b>, Chang Zheng Wang, Yi Zang, Jia Li*, Tony D James, Xiao-Peng He*. Supramolecular core–glycoshell polythiophene nanodots for targeted imaging and photodynamic therapy. Chemical Communications.<\/i> 2017, 53: (70), 9793-9796. <\/font><\/div>\n
7.Hai-Na Xie<\/font>#<\/sup><\/span>, Yu-Yuan Chen<\/span>#<\/sup><\/span>, Guo-Biao Zhu, <\/span>Hai-Hao Han<\/b>*, Xile Hu, Zhi-Qiang Pan, Yi Zang, Donghao Xie*, Xiao-Peng He, Jia Li*, Tony D. James*. Targeted delivery of maytansine to liver cancer cells via galactose-modified supramolecular two-dimensional glycomaterial. <\/span>Chemical Communications<\/i>. 2022, 58 (32), 5029-5032. <\/span><\/div>\n
8.Luling Wu<\/font>#<\/sup><\/span>, Jihong Liu<\/span>#<\/sup><\/span>, Xue Tian<\/span>#<\/sup><\/span>, Robin R. Groleau, Beidou Feng, Yonggang Yang, Adam C. Sedgwick, <\/span>Hai-Hao Han*<\/b>, Yang Wang, Han-Min Wang, Fang Huang, Steven D. Bull, Hua Zhang*, Chusen Huang*, Yi Zang, Jia Li, Xiao-Peng He, Ping Li*, Bo Tang, Tony D. James*, Jonathan L. Sessler*. Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5\'-triphosphate in Cellular Applications. <\/span>Journal of the American Chemical Society<\/i>. 2022, 144: (1), 174-183. <\/span><\/div>\n
9.Adam C Sedgwick<\/font>#<\/sup><\/span>, <\/span>Hai-Hao Han<\/b>#<\/sup><\/span>,<\/span> <\/span>Jordan E Gardiner, Steven D Bull*, Xiao-Peng He*, Tony D James*. The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH. <\/span>Chemical Science<\/i>. 2018, 9: (15), 3672-3676. <\/span><\/div>\n
10.Changzheng Wang<\/font>#<\/sup><\/span>, <\/span>Hai-Hao Han<\/b>#<\/sup><\/span>, Xinying Tang, Dongming Zhou*, Changfeng Wu, Guorong Chen, Xiao-Peng He*, He Tian. Sialylglycan-assembled supra-dots for ratiometric probing and blocking of human-infecting influenza viruses. <\/span>ACS Applied Materials & Interfaces.<\/i> 2017, 9: (30), 25164-25170. <\/span><\/div>\n
11.Wei-Tao Dou<\/font>#<\/sup><\/span>, <\/span>Hai-Hao Han<\/b>#<\/sup><\/span>, Adam C.Sedgwick, Guo-Biao Zhu, Yi Zang, Xin-Rong Yang*, Juyoung Yoon*, Tony D. James*, Jia Li*, Xiao-Peng He*. Fluorescent probes for the detection of disease-associated biomarkers.<\/span> Science Bulletin<\/i>. 2022, 67, 853-878. <\/span><\/div>\n
12.Maria Weber<\/font>#<\/sup><\/span>, <\/span>Hai-Hao Han<\/b>#<\/sup><\/span>, Bo-Han Li<\/span>#<\/sup><\/span>, Maria L. Odyniec, Charlotte E. F. Jarman, Yi Zang, Steven D. Bull, Amanda B. Mackenzie, Adam C. Sedgwick*, Jia Li*, Xiao-Peng He*, Tony D. James*. Pinkment: a synthetic platform for the development of fluorescent probes for diagnostic and theranostic applications.<\/span> Chemical Science<\/i>. 2020, 11: (32), 8567-8571. <\/span><\/div>\n
13.Lei Dong<\/font>#<\/sup><\/span>, Min-Yu Zhang<\/span>#<\/sup><\/span>, <\/span>Hai-Hao Han<\/b>#<\/sup><\/span>, Yi Zang, Guo-Rong Chen, Jia Li*, Xiao-Peng He*, Sébastien Vidal*. A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters. <\/span>Chemical Science<\/i>. 2022, 13: (1), 247-256. <\/span><\/div>\n
14.He Tian Jr.<\/font>#<\/sup><\/span>, Adam C. Sedgwick<\/span>#<\/sup><\/span>, <\/span>Hai-Hao Han<\/b>#<\/sup><\/span>, Sajal Sen, Guo-Rong Chen, Yi Zang, Jonathan L. Sessler*, Tony D. James*, Jia Li*, Xiao-Peng He*. Fluorescent probes for the imaging of lipid droplets in live cells. <\/span>Coordination Chemistry Reviews<\/i>. 2021, 427, 213577. <\/span><\/div>\n <\/font>","jyjl":"","gzjl":"
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